Pharmacology Weekly's: Medication and Herbal Table of Substrates, Inhibitors and Inducers of UGT Enzymes in Phase II Metabolism

Click to go to: UGT Inhibitors UGT Inducers

MEDICATION & HERBAL SUBSTRATES, INHIBITORS & INDUCERS OF UGT ENZYMES DRUG TABLE ©2010 Pharmacology Weekly Inc
SUBSTRATES
UGT1A1	UGT1A3	UGT1A4	UGT1A6	UGT1A8	UGT1A9	UGT1A10	UGT2B4	UGT2B7	UGT2B15
Acetaminophen Atorvastatin Buprenorphine Carvedilol Estradiol Etoposide Ezetimibe Febuxostat Fluvastatin Gemfibrozil Irinotecan Levothyroxine Losartan Lovastatin Ketoconazole Morphine Naltrexone Naphthol Paracetamol Raloxifene Raltegravir Rosuvastatin Simvastatin SN-38 Telmisartan	4-OH-tamoxifen Amitriptyline Atorvastatin Buprenorphine Chlorpromazine Clozapine Cyproheptadine Diclofenac Diphenhydramine Doxepin Ezetimibe Febuxostat Fluvastatin Gemfibrozil Ibuprofen Imipramine Losartan Lovastatin Loxapine Nalorphine Naloxone Naltrexone Naproxen Promethazine Rosuvastatin Simvastatin Valproate	4-OH-tamoxifen Amitriptyline Androsterone Asenapine Chlorpromazine Clozapine Cyclobenzaprine Cyproheptadine Diphenhydramine Doxepin Imipramine Irinotecan Lamotrigine Loxapine Meperidine Nicotine Olanzapine Progestins Promethazine Retigabine	Acetaminophen Entacapone Ketoprofen Naproxen Nefazodone Paracetamol	Morphine Mycophenolate Raloxifene	Acetaminophen Almokalant Clofibrate Dapsone Diclofenac Entacapone Estradiol Estrone Febuxostat Fenofibrate Flavopiridol Furosemide Gemfibrozil Ibuprofen Ketoprofen Labetalol Mycophenolate Naproxen Nicotine Paracetamol Propofol Propranolol SN-38 Retinoic acid Thyroxine Tolcapone Zidovudine	Furosemide Raloxifene Simvastatin SN-38	Carvedilol Codeine	Almokalant Atorvastatin Buprenorphine Carvediolol Chloramphenicol Clofibric acid Codeine Cyclosporine Diclofenac Entacapone Epirubicin Febuxostat Fenofibrate Fenoprofen Fluvastatin Gemfibrozil Hydromorphone Ibuprofen Ketoprofen Lamotrigine Lorazepam Methadone Morphine Mucophenolate Nalorphine Naloxone Naltrexone Naproxen Nicotine Oxazepam (r) Oxycodone Naloxone Simvastatin Tacrolimus Temazepam Valproic acid Zidovudine	Dienestrol Entacapone Estrogens Ezetimibe Gemfibrozil Lorazepam-s Oxazepam-s Testosterone Tolcapone


INHIBITORS
UGT1A1	UGT1A3	UGT1A4	UGT1A6	UGT1A8	UGT1A9	UGT1A10	UGT2B4	UGT2B7	UGT2B15
Atazanavir Gemfibrozil Indinavir Ketoconazole	Gemfibrozil							Ketoconazole Valproic acid
Herbals	Herbals	Herbals	Herbals	Herbals	Herbals	Herbals	Herbals	Herbals	Herbals
Silybum marianum Valeriana officinalis			Silybum marianum Valeriana officinalis		Silybum marianum Valeriana officinalis			Silybum marianum Valeriana officinalis	Silybum marianum Valeriana officinalis


INDUCERS
UGT1A1	UGT1A3	UGT1A4	UGT1A6	UGT1A8	UGT1A9	UGT1A10	UGT2B4	UGT2B7	UGT2B15
Carbamazepine Nicotine		Carbamazepine Nicotine	Carbamazepine Nicotine	Carbamazepine Nicotine	Carbamazepine Nicotine	Carbamazepine Nicotine	Barbiturates	Barbiturates	Barbiturates
Herbals	Herbals	Herbals	Herbals	Herbals	Herbals	Herbals	Herbals	Herbals	Herbals
Orthosiphon stamineus

Note: This table will be updated on an ongoing basis as new information is made known to us or come available. As a result, we welcome any input that you feel would improve or add value to the table so that all using it may benefit. If you would like to contribute or comment, please contact us

Disclaimer: For more information please click here

UGT Drug Reference Table: Substrates, Inhibitors, and Inducers. ©2010 Pharmacology Weekly Inc. All Rights Reserved.