Drug Interactions Newsletter

Volume 2, Issue 38, 10/06/2010

Question

Why should the protease inhibitor, atazanavir (Reyataz), be used with caution in combination with the histamine-2 (H2) receptor antagonist, ranitidine (Zantac)?

Answer

The current standard of care for the treatment of human immunodeficiency virus (HIV) infection is combined antiretroviral therapy.  One common component to this combination regimen includes the use of protease inhibitors (PI), such as atazanavir (Reyataz).1  Unfortunately, many HIV infected patients have gastrointestinal disorders, such as...

.......To read the full answer please LOGIN or SUBSCRIBE NOW.