Drug Interactions Newsletter

Volume 1, Issue 41, 10/27/2009

Question

What effect does the antibiotic clarithromycin (Biaxin®) have on the cytochrome P450 (CYP) 3A4 enzyme?

Answer

Clarithromycin (Biaxin®) is a well known macrolide antibiotic used in the management of Helicobacter pylori, uncomplicated skin, and upper and lower respiratory tract infections.(1)  Unfortunately, clarithromycin can cause drug interactions because of its ability to...

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