Pharmacology Weekly

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Natural Medicines Newsletter

Volume 1, Issue 28, 07/30/2009

Question

What is the mechanism of action by which Misai kucing or Java Tea (Orthosiphon stamineus Benth) decreases serum uric acid levels in patients with gout?

Answer

Misai kucing or Java Tea (Orthosiphon stamineus Benth) is a common herb derived from a shrub in Southeast Asia, in particular Indonesia and Malaysia.(1,2)  It has been known to have many different active ingredients that exert biologic activities that are known to be used as a diuretic or for arthritis, inflammation, diabetes, and gout.(1-6)  Of the many ingredients from Misai kucing, caffeic acid derivatives have been identified as one of many contributors.(4)

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